ResearchCity Key Papers — 19 Published Scientific Papers (1991–2018)

The peer-reviewed scientific foundation behind the Matheo papers and ResearchCity claims — from age 17 to full professor.

These 19 papers establish the scientific credentials behind the LLoL project. The Matheo papers make claims rooted in evolutionary systems biology, Evolvix, population genetics, and computational biology. This collection provides the peer-reviewed evidence for readers who want to check whether LLoL has the scientific background to make those claims.

Highlights

• Published in Science (2003) — highest-impact journal in the collection

• Framework-defining papers — EvoSysBio (2009, 2012, 2016), Evolvix BEST Names (2017)

• Directly relevant to Jubilee System — Lazy Updating (2014) implies the core algorithm for Jubilee measuring

• Directly relevant to POST system — Evolvix BEST Names (2017) is the scientific foundation for naming conventions

• 35+ years of scientific work — from Jugend Forscht (1991) to Complexity journal (2018)

• Collaborations with leading scientists — Brian Charlesworth, William G. Hill, Jane Hillston, and 34 co-authors on the Evolvix paper

All 19 papers (chronological)

Year	Title	Venue	Pages	Type
1991	Electric Spark Productivity in Miller Experiments	Jugend Forscht	15	study
2002	Evolutionary Bioinformatics — Dissertation	TU München (PhD thesis)	444	diss
2002	Global Computing for Bioinformatics	Briefings in Bioinformatics	12	review
2003	High Deleterious Mutation Rate in Stationary Phase E. coli	Science 302: 1558–1560	17	study
2006	Distribution of Mutational Effects in Drosophila	Biology Letters 2: 426–430	6	study
2006	Genomic Decay Paradox in Human mtDNA	Genetic Research 87: 133–159	27	study
2007	Background Selection in Single Genes	Genetics 175: 1381–1393	13	study
2007	Evolution@home — Low-Effort Global Computing	Software: Practice and Experience 37: 1289–1318	30	study
2008	DME in a Simple Circadian Clock	LNBI 5307: 156–175 (CMSB 2008)	20	study
2009	A Framework for Evolutionary Systems Biology	BMC Systems Biology 3:27	34	review
2009	SBGN-PD Process Flow with Bio-PEPA	EPTCS 6: 93–107	15	study
2009	SBGNtext2BioPEPA Technical Report	Edinburgh Tech Report EDI-INF-RR-1334	29	techreport
2010	Population Genetics of Mutations — Introduction	Phil. Trans. R. Soc. B 365: 1153–1167	15	review
2012	EvoSysBio, Adaptive Landscapes & DME	Adv. Exp. Med. Biol. 751: 399–	12	review
2014	Lazy Updating for Stochastic Simulations	Chem. Phys. 141: 204109	20	study
2014	Reproducibility in Large-Scale Computing	XSEDE14 Workshop Report	16	report
2016	Systems in Evolutionary Systems Biology	Enc. Evol. Biol. 4: 297–318	22	study
2017	Evolvix BEST Names for Semantic Reproducibility	Ann. N.Y. Acad. Sci. 1387: 124–144	95	study
2018	Cooperation in a Two-Level Snowdrift Game	Complexity 2018: 9836150	14	study

Key papers for the Matheo series

These papers are most directly relevant to claims made in the Matheo paper series:

• Ehlert & Loewe 2014 — Lazy Updating implies the core algorithm for Jubilee measuring (directly relevant to Jubilee System claims)

• Loewe 2009, 2016 — EvoSysBio framework and encyclopedia entry (the scientific methodology behind modeling claims)

• Loewe et al. 2017 — Evolvix BEST Names (directly relevant to POST system and language design)

• Loewe 2002 — 444-page dissertation (the deepest scientific root)

• Loewe 1991 — Jugend Forscht study (earliest scientific work, age ~17)