.. meta::
   :description: AI overview of the Genetics 546 course flyer — "Evolutionary Systems Biology Modeling Introduction" at UW-Madison, designed and taught by Laurence Loewe since Fall 2018.
   :keywords: Genetics 546, EvoSysBio, teaching, course flyer, modeling, Evolvix, UW-Madison, Loewe, interdisciplinary, active learning, MMv3
   :og:card:title: Teaching Flyer<br>Genetics 546 EvoSysBio
   :og:card:description: 1-page course flyer for Genetics 546 — "Evolutionary Systems Biology Modeling Introduction" at UW-Madison, by Laurence Loewe.

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.. title:: Teaching Flyer — Genetics 546


****************************************************************************************************
Teaching Flyer — Genetics 546 EvoSysBio Modeling Introduction
****************************************************************************************************

*"You name it. You model it. You map it." — a visually striking invitation to interdisciplinary biological modeling.*


.. admonition:: Download the original document (PDF)
   :class: note

   `Genetics 546 Course Flyer — PDF (1.9 MB) </_file/pdf/gnp/mmv3/dusty-deep-data/loewe-about-me-science/loewe-2018-teach-intro-evosysbio-fall-course-genetics546-flyer-2018m04d05-page.pdf>`__
   — 1 page, :doc:`Jonah License with CC0 Public Domain </license/joli/index>`

   Filename: ``loewe-2018-teach-intro-evosysbio-fall-course-genetics546-flyer-2018m04d05-page.pdf``

   `WebP preview (328 KB) </_file/pdf/gnp/mmv3/dusty-deep-data/loewe-about-me-science/loewe-2018-teach-intro-evosysbio-fall-course-genetics546-flyer-2018m04d05-page.webp>`__

   Also in this folder: :doc:`Teaching Syllabus <loewe-2018-teaching-syllabus>` (the full 14-page syllabus for this course)


.. image:: /_file/pdf/gnp/mmv3/dusty-deep-data/loewe-about-me-science/loewe-2018-teach-intro-evosysbio-fall-course-genetics546-flyer-2018m04d05-page.webp
   :alt: Genetics 546 Course Flyer — Evolutionary Systems Biology Modeling Introduction
   :width: 100%
   :align: center


|


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Abstract
========

A 1-page promotional flyer for **Genetics 546: Evolutionary Systems
Biology Modeling Introduction**, a 3-credit course at UW-Madison
designed and taught by Laurence Loewe. The flyer features a striking
circular genome/interaction diagram (image: Martin Krzywinski/EMBO)
and the motto "Models are the maps of modern biology."

The course promises:

- Pick your own research topic in interdisciplinary groups
- Problem-based active learning environment
- Learn the 5 W's of modeling: What system, Which parts, When
  actions occur, Where, and Why
- Use Evolvix, a modeling tool designed for accessibility and
  mathematical accuracy
- One-on-one help from an expert with 20+ years of modeling experience
- Learn grant writing instead of taking exams
- "Must Have Skills for the biology of the future"

**Prerequisite:** Only an interest in interdisciplinary approaches to
modeling in biology. Open to undergraduates and graduate students from
Biology, Medicine, Chemistry, Physics, Math, Stats, Computer Science,
and Engineering.

Schedule: Tuesday lecture 4--5:15pm, Thursday lab 4--6pm. Annual
offering since Fall 2018. Topics spiral from molecules in cells to
individuals in ecosystems to cancer evolution to long-term evolution.


Broader Significance (Claude's Assessment)
============================================

1. **Teaching side of the research program.** This flyer represents the
   broader impact vision from the NSF CAREER grant made real. The
   promise to "dissolve the barrier between teaching-toys and real
   tools" materialized as a course where students use the same Evolvix
   platform that powers research-grade simulations.

2. **Interdisciplinary philosophy.** The open enrollment policy
   (any field related to biology) and the emphasis on "making
   connections" across disciplines reflects the same cross-boundary
   thinking that characterizes the Matheo papers and the broader LLoL
   project.

3. **Grant-writing pedagogy.** Replacing exams with grant proposals
   is a distinctive pedagogical choice: students learn to articulate
   research value, not just recall facts. This is unusual at the
   undergraduate level and aligns with the ZION cycle principle
   of learning by doing real work.


Key Concepts at a Glance
==========================

.. list-table::
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   * - **Genetics 546**
     - UW-Madison course: Evolutionary Systems Biology Modeling
       Introduction, 3 credits, annual since Fall 2018
   * - **5 W's of Modeling**
     - What system, Which parts, When actions occur, Where, and Why —
       the course's framework for building biological models
   * - **Evolvix**
     - The modeling tool used in the course, designed to be accessible
       and mathematically accurate
   * - **Active learning**
     - Problem-based approach: students pick topics, build models,
       write grants instead of taking exams
   * - **Open enrollment**
     - No formal prerequisites beyond interest — deliberately
       interdisciplinary across science and engineering fields


Document Information
=====================

.. list-table::
   :widths: 30 70
   :header-rows: 0

   * - **Document ID**
     - Course Flyer (About-Me Science, Dusty Deep Data)
   * - **Full title**
     - Genetics 546 — Evolutionary Systems Biology Modeling Introduction
   * - **Author**
     - Laurence Loewe
   * - **Date**
     - 2018m04d05 (v2r0)
   * - **Format**
     - 1-page promotional flyer with circular visualization
   * - **License**
     - :doc:`Jonah License with CC0 Public Domain </license/joli/index>`
   * - **Part of**
     - Good News Pack MMv3, Dusty Deep Data / About-Me Science
   * - **PDF size**
     - 1.9 MB
   * - **WebP size**
     - 328 KB

Related documents in the Good News Pack:

- :doc:`Teaching Syllabus <loewe-2018-teaching-syllabus>` (full 14-page syllabus for this course)
- :doc:`NSF CAREER Grant <loewe-2011-nsf-grant>` (the grant whose broader impact vision produced this course)
- :doc:`2009 — EvoSysBio Framework </good-news-pack/vv/mmv3/dusty-deep-data/loewe-researchcity-key-papers/loewe-2009-evosysbio-framework>` (the paper defining the field this course teaches)


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